Suprello™ Surgical Wound Matrix

‍Rapid Tissue Resorption for Sustained Wound Closure

Suprello™ surgical wound matrix rapidly resorbs and integrates into the host tissue to encourage healing by primary intention³. Suprello™ facilitates healing at the reapproximated incision margins by supporting complete tissue apposition and robust re-epithelialization for effective and sustained wound closure (see Figure 1).

Intimate Contact and Tissue Compatibility

Suprello™ flowable formulation offers optimal contact with the incision margins, creating an environment that supports healing through primary intention. The porous surgical wound matrix allows diffusion of oxygen and nutrients⁵, enabling cell infiltration at the surgical site to support wound healing⁶.

Strong Antibacterial Protection

Suprello™ provides inherent broad-spectrum antibacterial protection effective against multidrug-resistant organisms (MDROs)¹, minimizing the risk of infection in high-risk surgical cases (see Figure 2). Suprello™ contains cationic peptides that provide strong antibacterial protection by interacting with and destabilizing bacterial membranes^1,2. This innovative, physical mechanism of antibacterial protection overcomes local and systemic tissue toxicity while also minimizing the risk of antibacterial resistance, often associated with the use of antibiotics and antimicrobial agents.

Product Benefits

• Rapid tissue integration, supporting complete tissue apposition and sustained wound closure³.
• Strong broad-spectrum antibacterial protection against MDROs, minimizing the risk of developing infection in high-risk surgical cases^1,2. 
• Shelf-stable at room temperature for three years. 
• Ready-to-use, eliminating the need for mixing, hydration, or reconstitution. 
  

Suprello™ is FDA 510(k) cleared, and available by prescription only under the supervision of a healthcare professional for the local management of partial and full-thickness surgical wounds.

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_REFERENCES

_{1. Data on File, RR-0004}

_{2. Data on File, RR-0003}

_{3. Data on File (GM-2101)}

_{4. FDA 510k submission package}

_{5. Data on File, RR-0005}

_{6. Data on File, RR-0001}