G4Derm™ Plus

Powered by Self-Assembling Peptides (SAP) to revitalize complex wounds

G4Derm™ Plus is a fully synthetic resorbable biomimetic matrix (BMM™) designed to support wound closure in complex, hard-to-heal wounds by promoting rapid granulation tissue formation. The synthetic peptides in G4Derm™ Plus self-assemble to create an extracellular matrix (ECM)-like scaffold that facilitates tissue regrowth and revascularization, while also offering broad-spectrum antibacterial protection. G4Derm™ Plus creates an optimal healing environment for complex and chronic wounds, and represents a significant advancement in wound care, offering numerous benefits as it promotes effective wound stabilization and progression toward closure, directly improving patient outcomes.

• Full-wound bed coverage, contours to the shape of the wound bed, and gradually integrates into host tissue to encourage regrowth and revascularization.¹
• Granulation tissue formation within just 1-2 applications, even in deep wounds with exposed structures, such as tendon and bone.^*2-4
• 2x faster wound closure rates compared to advanced biologics in diabetic foot ulcers (DFUs).^2*
• Strong broad-spectrum antibacterial protection against MDROs to manage bioburden⁵ and prevent biofilm reformation,^6-7 without causing local tissue toxicity.
• Ready-to-use prefilled syringe eliminates the need for mixing or reconstitution, enabling seamless dispensing into wound bed with a flexible applicator tip for precise delivery.
• Fully synthetic, shelf stable at room temperature for 3 years.⁸
• 510(k) clearance #K222025: synthetic wound matrix for the local management of partial and full-thickness wounds (e.g., DFU, VLU, pressure ulcers, first-degree and second-degree burns).