NATROX® O2 Continuous Topical Oxygen Therapy

Using the natural properties of oxygen to heal wounds faster

NATROX® O2 is a wearable medical device designed to continuously deliver topical oxygen directly to a wound to promote and enhance healing. Battery-powered, portable, and completely silent, the discreet device is easy to manage and practical for everyday use, allowing patients to continue their normal daily activities. This low-flow tissue oxygenation system is intended as an adjunct to the standard of care by providing the vital properties of oxygen to a wide range of chronic, non-healing wounds. Through a process of water electrolysis, the NATROX® O­­­2 Oxygen Generator (OG) creates a flow of highly concentrated oxygen, which is delivered to the wound using the NATROX® O­­­2 Oxygen Delivery System (ODS). The sterile, single-use ODS has a soft, pliable “wheel” shape that allows optimal oxygen flow and conformability to the wound bed. This ensures comfort for the patient while allowing free passage of wound exudate into the secondary dressing. NATROX® O­­­2 can be used during any phase of healing, is non-invasive, portable, and highly effective.

  • Patients with a chronic wound have a 71% greater chance of healing using NATROX® O2 topical oxygen therapy than with standard of care alone1
  • 24/7 oxygen delivery to the wound bed at a rate of 11ml/hr stimulates healing in previously non-healing wounds
  • Small, wearable, lightweight, and discreet, allowing for complete freedom of movement and reducing negative impacts to patient quality of life
  • Compatible with most standard secondary dressings
  • Oxygen Generator is powered by one of two rechargeable batteries that are interchanged every 24 hours

The Importance of Oxygen in Healing

Oxygen kickstarts healing by promoting previously stalled growth factors, building new tissue (i.e., collagen, protein), and helping to remove biofilms and antibacterial activities. All cellular activities are oxygen dependent:

  • Angiogenesis and revascularization
  • Cell metabolism and energy production
  • Antibacterial activities
  • Promotion of growth factors and signaling transduction
  • Collagen synthesis
  • Cell proliferation and re-epithelialization
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  Moelleken M, Jockenhöfer F, Benson S, Dissemond J. Prospective clinical study on the efficacy of bacterial removal with mechanical debridement in and around chronic leg ulcers assessed with fluorescence imaging. Int Wound J. 2020 Aug;17(4):1011-1018.
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What to Expect During NATROX® O₂ Therapy

REFERENCES

1. Serena TE, Bullock NM, Cole W et al. Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled trial. J Wound Care 2021; 30: Suppl.5 S7-14

2. Yu J, et al. (2016) Wound Repair Regen. 24:1066-1072

3. Lee A. (2101) Continuous Topical Oxygen Therapy - Improving Healing in the Diabetic Foot [Poster] DFCon

Key Features

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All necessary regulatory documentation, instructions for use, published studies, patient education tools, etc. (as applicable) can be provided upon request by contacting cs@spartanmedical.com or (888) 240-8091. We are available at any time to meet with providers and staff to answer any questions about Spartan Medical’s entire portfolio of advanced medical solutions.

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