NervAlign® Nerve Cuff by ReNerve Ltd.
The NervAlign® Nerve Cuff is a non-constrictive implant made from porcine pericardium that protects peripheral nerves by creating a biocompatible interface between the nerve and surrounding tissue. Processed using a proprietary eCOO® technology, it delivers cleaner and better quality acellular collagen structure that supports cellular attachment and minimizes immunogenic risk.
- Fully bio-absorbed within 6 months
- Antigen free
- Non-toxic processing using eCOO technology
- Non-constrictive protection for nerves
- Ultra-thin
- Semipermeable
- Highly pliable and conformable
- No special storage requirements

Clinical Comparison of NervAlign® vs. Standard of Care
The NervAlign® Nerve Cuff significantly reduces post-operative pain compared to standard surgical methods demonstrating higher patient satisfaction with improved recovery.1
Proprietary eCOO® Technology
The NervAlign® Nerve Cuff leverages proprietary eCOO® Technology—supercritical CO₂ processing—to produce a cleaner, better quality tissue. This advanced processing method:
- Achieves deep microstructural penetration
- Preserves the natural crosslinking of the ECM structure
- Promotes cellular attachment
- Minimizes immunogenic responses

Key Features
REFERENCES
1. Namany et al. Efficacy of a porcine pericardium nerve wrap in peripheral nerve surgery, March 2025, ACFAS 2025, Link
All necessary regulatory documentation, instructions for use, published studies, patient education tools, etc. (as applicable) can be provided upon request by contacting cs@spartanmedical.com or (888) 240-8091. We are available at any time to meet with providers and staff to answer any questions about Spartan Medical’s entire portfolio of advanced medical solutions.
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